Plenty of players will be looking to prove themselves as the Whites hope to continue the strong start to their Australia tour made by a 2-1 win over A-League club Brisbane Roar.
Fans travelling to the Suncorp Stadium to take in the Villa clash can expect to see lots of old faces and a few newer ones, as Jesse Marsch works on integrating his six summer signings into the squad.
Here's how we think Leeds could line-up against the Birmingham side....
1. GK - Illan Meslier
Jesse Marsch told us in midweek that his number one would be involved and Meslier played a full part in training on Saturday. Photo: Robbie Jay Barratt
2. RB - Rasmus Kristensen
Expect the Dane to get at least 45 minutes, probably from the start, with Cody Drameh also set to feature. Photo: Bradley Kanaris
3. LB - Leif Davis
Came off the bench at the break in midweek but could be in line for a start. Was delivering the ball from the left during a training exercise on Saturday. Photo: Albert Perez
4. CB - Diego Llorente
Only got 30 minutes against the Roar so is due for more against Villa. Marsch is trying to give everyone a similar amount of action. Photo: Craig Mercer
5. CB - Leo Hjelde
The youngster is yet to feature, while Struijk got 90 and Koch 60 minutes against the Roar. If he's fit enough Hjelde could get a start. Photo: Clive Brunskill
6. CM - Marc Roca
Played the first half against the Roar and looks set to play a big part this season so another start would be no shock. Photo: Marc Adams